193684-79-6Relevant academic research and scientific papers
New crystalline N-(coumarin-4-yl)-L-pyroglutamic acid. The first synthesis and application to1H NMR optical purity determination of alcohols and ahines
Nagasawa, Kazuo
, p. 1047 - 1050 (2007/10/03)
Condensation of 3-phenylsulfonyl-4-chlorocoumarin with tertbutyl L-pyroglutamate potassium salt followed by desulfonylation and ester-cleavage yielded the novel crystalline N-(coumarin-4-yl)-L-pyroglutamic acid[CPYRO-OH], which being evidenced to be a versatile and reliable 1 H nmr optical purity determination agent for chiral alcohols and amines.
