193744-08-0Relevant articles and documents
3,6-Disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles: Synthesis and evaluation for antimicrobial and antiviral activity. III
Invidiata,Furno,Simoni,Lampronti,Musiu,Milia,Scintu,La Colla
, p. 259 - 261 (2007/10/03)
A series of novel 3,6-disubstituted 1,2,4-triazolo[3,4- b][1,3,4]thiadiazole derivatives was prepared and tested to evaluate their antimycotic, antibacterial and anti-HIV-1 activities. The reaction of thiocarbohydrazide with carboxylic acids at the melting temperature allows an improved preparation of the 5-substituted 4-amino-3-mercapto-1,2,4-triazole heterocycles which in turn allows an easier preparation of the 1,2,4- triazolo[3,4-b] [1,3,4]thiadiazole ling system. All tested compounds didn't show any significant activity.