193746-75-7

Basic information

• Product Name: SB242235
• Synonyms: SB242235;4-[4-(4-Fluorophenyl)-1-(4-piperidinyl)-1H-imidazol-5-yl]-2-methoxypyrimidine;4-(4-(4-Fluorophenyl)-1-(piperidin-4-yl)-1H-iMidazol-5-yl)-2-MethoxypyriMidine
• CAS NO: 193746-75-7
• Molecular Formula: C19H20FN5O
• Molecular Weight: 353.4
• Mol File: 193746-75-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 568.4±60.0 °C(Predicted)
• Appearance: /
• Density: 1.34
• Storage Temp.: 2-8°C(protect from light)
• PKA: 9.91±0.10(Predicted)
• CAS DataBase Reference: SB242235(CAS DataBase Reference)
• NIST Chemistry Reference: SB242235(193746-75-7)
• EPA Substance Registry System: SB242235(193746-75-7)

Safety Data

• Hazardous Substances Data: 193746-75-7(Hazardous Substances Data)

Usage

Description

SB242235 is a potent and selective inhibitor of p38 MAP kinase, a protein that significantly influences cellular responses to stress and inflammation. This chemical compound is primarily utilized in scientific research to investigate the role and function of p38 MAP kinase in various biological processes and disease states. It is recognized for its anti-inflammatory effects due to its capacity to inhibit the production of certain proteins and cytokines.

Uses

Used in Scientific Research:
SB242235 is used as a research tool for studying the role of p38 MAP kinase in biological processes and disease states. It aids in understanding the mechanisms of cellular responses to stress and inflammation.
Used in Anti-inflammatory Applications:
SB242235 is used as an anti-inflammatory agent due to its ability to inhibit the production of proteins and cytokines involved in inflammation. This property makes it a potential candidate for therapeutic interventions in inflammatory conditions.
Used in Pharmaceutical Development:
SB242235 is used as a potential therapeutic agent for treating diseases such as rheumatoid arthritis and other inflammatory conditions. Its potential applications in this area are currently being explored through scientific research and clinical studies.
Used in Drug Delivery Systems:
While not explicitly mentioned in the provided materials, it can be inferred that SB242235, like other compounds with therapeutic potential, could be incorporated into drug delivery systems to improve its bioavailability, targeting, and therapeutic outcomes in treating inflammatory conditions.

Relevant articles and documents

Substituted imidazole compounds

Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.