193753-48-9Relevant academic research and scientific papers
Parallel synthesis of modular chiral Schiff base ligands and evaluation in the titatium(IV) catalyzed asymmetric trimethylsilylcyanation of aldehydes
Rodriguez, Belen,Pasto, Mireia,Jimeno, Ciril,Pericas, Miquel A.
, p. 151 - 160 (2007/10/03)
Highly modular tridentate Schiff base ligands arising from enantiopure epoxyalcohols have been prepared and evaluated in catalysis using parallel methods. The key structural motifs and experimental parameters have been identified, allowing enantioselectivities of up to 77% ee in the titatium-catalyzed trimethylsilyl cyanide addition to aldehydes.
Enantioselective aromatic Claisen rearrangement
Ito, Hisanaka,Sato, Azusa,Taguchi, Takeo
, p. 4815 - 4818 (2007/10/03)
The development of a highly enantioselective aromatic Claisen rearrangement was achieved by the reaction of catechol motto allylic ethers with chiral boron reagent 1. This system was also shown to avoid the formation of para rearrangement and abnormal Claisen rearrangement products.
