193901-08-5Relevant academic research and scientific papers
Structure-activity relationships, kinetics, selectivity, and mechanistic studies of synthetic hydraphile channels in bacterial and mammalian cells
Leevy, W. Matthew,Gammon, Seth T.,Levchenko, Tatiana,Daranciang, David D.,Murillo, Oscar,Torchilin, Vladimir,Piwnica-Worms, David,Huettner, James E.,Gokel, George W.
, p. 3544 - 3550 (2005)
Hydraphile compounds are shown to be cytotoxic to Gram-negative and Gram-positive bacteria, yeast, and mammalian cells. Their cellular toxicity compares favorably with other synthetic ionophores and rivals that potency of natural antibiotics. The effects
