193904-60-8Relevant articles and documents
Chemoselective, enzymatic C-H bond amination catalyzed by a cytochrome P450 containing an Ir(Me)-PIX cofactor
Dydio, Pawel,Key, Hanna M.,Hayashi, Hiroki,Clark, Douglas S.,Hartwig, John F.
supporting information, p. 1750 - 1753 (2017/02/15)
Cytochrome P450 enzymes have been engineered to catalyze abiological C-H bond amination reactions, but the yields of these reactions have been limited by low chemoselectivity for the amination of C-H bonds over competing reduction of the azide substrate t
Cobalt-catalyzed intramolecular C-H amination with arylsulfonyl azides
Ruppel, Joshua V.,Kamble, Rajesh M.,Zhang, X. Peter
, p. 4889 - 4892 (2008/03/14)
(Chemical Equation Presented) Cobalt complexes of porphyrins are effective catalysts for intramolecular C-H amination with arylsulfonyl azides. The cobalt-catalyzed process can proceed efficiently under mild and neutral conditions in low catalyst loading
Rhodium(II)-Catalyzed CH Insertions with imino>phenyl-λ3-iodane
Naegeli, Ivo,Baud, Corine,Bernardinelli, Gerald,Jacquier, Yvan,Moran, Mary,Mueller, Paul
, p. 1087 - 1105 (2007/10/03)
The catalyzed decomposition of imino>phenyl-λ3-iodane (NsN=IPh) resulted in formal insertions into CH bonds, activated by phenyl or vinyl groups, or by O-substituents.Scope and limitations of the reaction were investigated.Yields of up to 84percent were achieved in the most favorable cases.Yields were enhanced by electron-releasing substituents and decreased by steric hindrance.Aziridination competed with allylic insertion with olefinic substrates.The insertion reaction proceeded with retention of configuration.With chiral RhII catalysts, a modest asymmetric induction was observed.A mechanism involving direct insertion by a Rh-complexed nitrene into the CH bond is proposed.