193953-76-3

Basic information

• Product Name: (S)-2-[(4S,5R,6S)-6-((R)-2-Benzyloxy-1-methyl-ethyl)-2,2-di-tert-butyl-5-methyl-[1,3,2]dioxasilinan-4-yl]-propionaldehyde
• Synonyms: (S)-2-[(4S,5R,6S)-6-((R)-2-Benzyloxy-1-methyl-ethyl)-2,2-di-tert-butyl-5-methyl-[1,3,2]dioxasilinan-4-yl]-propionaldehyde
• CAS NO: 193953-76-3
• Molecular Weight: 434.692
• Mol File: 193953-76-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-[(4S,5R,6S)-6-((R)-2-Benzyloxy-1-methyl-ethyl)-2,2-di-tert-butyl-5-methyl-[1,3,2]dioxasilinan-4-yl]-propionaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-[(4S,5R,6S)-6-((R)-2-Benzyloxy-1-methyl-ethyl)-2,2-di-tert-butyl-5-methyl-[1,3,2]dioxasilinan-4-yl]-propionaldehyde(193953-76-3)
• EPA Substance Registry System: (S)-2-[(4S,5R,6S)-6-((R)-2-Benzyloxy-1-methyl-ethyl)-2,2-di-tert-butyl-5-methyl-[1,3,2]dioxasilinan-4-yl]-propionaldehyde(193953-76-3)

Safety Data

• Hazardous Substances Data: 193953-76-3(Hazardous Substances Data)

Upstream product

• 160238-46-0 (2R)-3-(4-methoxybenzyloxy)-2-methyl-1-propanal 
• 85272-31-7 di-tert-butylsilyl bis(trifluoromethanesulfonate) 
• 193749-56-3 (R)-2-[(4R,5S,6S)-6-((R)-2-Benzyloxy-1-methyl-ethyl)-2,2-di-tert-butyl-5-methyl-[1,3,2]dioxasilinan-4-yl]-propan-1-ol 

Relevant articles and documents

Total synthesis of (-)-(6S,7S,8S,9R,10S,2'S)-membrenone-A and (-)-(6S,7S,8S,9R,10S)- membrenone-B and structural assignment of membrenone-C.

[reaction: see text] (-)-(6S,7S,8S,9R,10S,2'S)-Membrenone-A and (-)-(6S,7S,8S,9R,10S)-membrenone-B were prepared in 11 steps (3% and 2.4% overall yield, respectively). Key steps included a tin(II)-mediated aldol followed by a syn selective reduction, givi