19396-06-6

Usage

Uses

Used in Agricultural Industry:
Polyoxin B is used as a fungicide for the protection of crops, particularly against Alternaria leaf spot, a common fungal disease that affects a wide range of agricultural products. Its application helps in reducing crop losses and maintaining the quality of produce.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Polyoxin B is utilized as a fungicide in the development of pesticides and other antifungal treatments. Its effectiveness against various fungal pathogens makes it a crucial component in the formulation of products aimed at controlling fungal infections and diseases.

InChI:InChI=1/C17H25N5O13/c18-6(8(25)5(24)3-34-16(19)32)13(29)20-7(15(30)31)11-9(26)10(27)14(35-11)22-1-4(2-23)12(28)21-17(22)33/h1,5-11,14,23-27H,2-3,18H2,(H2,19,32)(H,20,29)(H,30,31)(H,21,28,33)

Upstream product

• 90661-54-4 5-O-(aminocarbonyl)-2-[((1,1-dimethylethyl)oxycarbonyl)amino]-2-deoxy-3,4-O-(1-methylethylidene)-L-xylonic acid 
• 127646-37-1 5-hydroxymethyl-1-(methyl 2',3'-di-O-acetyl-5'-azido-5'-deoxy-β-D-allofuranosyluronate)uracil 
• 21027-33-8 1-(5'-amino-5'-deoxy-β-D-allofuranosyluronic acid)-5-hydroxymethyluracil 
• 155154-68-0 methyl (5-azido-5-deoxy-1,2,3-tri-O-acetyl-D-allofuranosid)uronate 
• 310904-41-7 5-hydroxymethyl-1-(methyl 2',3'-di-O-acetyl-5'-carbobenzyloxyamino-5'-deoxy-β-D-allofuranosyluronate)uracil 
• 205449-15-6 Benzyl 5-O-(aminocarbonyl)-2-(tert-butoxycarbonyl)amino-2-deoxy-3,4-O-isopropylidene-L-xylonate 
• 172847-83-5 (S)-tert-Butoxycarbonylamino-((4S,5S)-5-carbamoyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 31517-04-1 5-trimethylsiloxymethyl-2,4-bis(trimethylsiloxy)pyrimidine 
• 4433-40-3 5-hydroxymethyl uracil 
• 310904-43-9 (S)-[(S)-2-tert-Butoxycarbonylamino-2-((4S,5S)-5-carbamoyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-acetylamino]-[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-hydroxymethyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-yl]-acetic acid 

Relevant academic research and scientific papers

First total syntheses of (+)-polyoxin B and (+)-Polyoxin D

First total syntheses of the peptidyl nucleoside antibiotics, polyoxins B (1) and D (2), are achieved based on the coupling reactions of the N-protected L-carbamoyl-polyoxamic acid derivative (6) with polyoxin C (8), 6 with polyoxin C acid (9), respectively.