19398-06-2

Basic information

• Product Name: 2-Ethylphenylhydrazine hydrochloride
• Synonyms: 2-ethvlphenvlhvdrazine,hvdrochloride;2-ETHYLPHENYLHYDRAZINE HYDROCHLORIDE, 98 %;2-ETHYLPHENYLHYDRAZINE HYDROCHLORIDE 98%;2-Ethylphenylhydrazin HCL;o-ethylphenylhydrazine,hydrochloride;2-Ethylphenylhydrazine hydrochloride;2-Ethylphenylhydrazine monohydrochloride;O-Ethylphenylhydrazine Monochloride
• CAS NO: 19398-06-2
• Molecular Formula: C₈H₁₂N₂*ClH
• Molecular Weight: 172.66
• EINECS: 421-460-2
• Product Categories: Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes;Hydrazines;Nitrogen Compounds;Organic Building Blocks
• Mol File: 19398-06-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 178 °C (dec.)(lit.)
• Boiling Point: 247.7 °C at 760 mmHg
• Flash Point: 118.9 °C
• Appearance: almost white to beige fluffy powder
• Density: 1.21
• Vapor Pressure: 0.0253mmHg at 25°C
• Refractive Index: 1.603
• Solubility: water: soluble
• Sensitive: Hygroscopic
• BRN: 3697547
• CAS DataBase Reference: 2-Ethylphenylhydrazine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Ethylphenylhydrazine hydrochloride(19398-06-2)
• EPA Substance Registry System: 2-Ethylphenylhydrazine hydrochloride(19398-06-2)

Safety Data

• Hazard Codes: Xn,N,T
• Statements: 22-36/37/38-43-50/53-48/25-41-40
• Safety Statements: 26-36/37-60-61-45-36/37/39-22
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 3
• F: 1-10
• HazardClass: 9
• Hazardous Substances Data: 19398-06-2(Hazardous Substances Data)

Usage

Chemical Properties

almost white to beige fluffy powder

General Description

2-Ethylphenylhydrazine hydrochloride is a hydrazine derivative.

InChI:InChI=1/C8H12N2/c1-2-7-5-3-4-6-8(7)10-9/h3-6,10H,2,9H2,1H3

Upstream product

• 578-54-1 ortho-ethylaniline 

Downstream Products

• 41340-36-7 7-ethyl-2-(1H-indol-3-yl)ethan-1-ol 
• 1226954-31-9 C₁₂H₁₈N₂O 
• 19275-56-0 8-ethyl-2,3,4,9-tetrahydrocarbazole 
• 792953-03-8 5-amino-1-(2-ethylphenyl)-1H-pyrazole-4-carbonitrile 
• 591752-29-3 (1-carbamoylmethyl-8-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid methyl ester 
• 591752-28-2 (8-ethyl-1-methoxycarbonylmethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid 
• 591752-27-1 (1-carboxymethyl-8-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid 
• 591752-25-9 3-(1-cyano-8-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)propionic acid ethyl ester 
• 591752-24-8 (1-chloromethyl-8-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid ethyl ester 
• 591752-30-6 (1-cyanomethyl-8-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid methyl ester 
• 591752-32-8 3-(1-cyano-8-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)propionic acid 
• 591752-34-0 8-ethyl-1-(3-hydroxypropyl)-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-carbonitrile 
• 591752-35-1 1-(3-bromopropyl)-8-ethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-carbonitrile 

Relevant articles and documents

Continuous-Flow Process for the Synthesis of 2-Ethylphenylhydrazine Hydrochloride

An expeditious process for the synthesis of 2-ethylphenylhydrazine hydrochloride via a continuous-flow reactor from 2-ethylaniline in 94% yield was described. The main steps in this synthesis involved not only the generation of diazonium salt intermediate in situ but also the temperature-programmed reduction by sodium sulfite in the tandem loop reactor. Total residence time was reduced to less than 31 min by increasing the reaction temperature and thereby taking advantage of improved mass and heat transfer of a continuous-flow system. The purification process was simplified by extraction of impurities in situ.

Synthesis, crystal structure and fungicidal activities of new type oxazolidinone-based strobilurin analogues

A series of oxazolidinone-based strobilurin analogues were efficiently synthesized by the reaction of 3-(2-bromomethylphenyl) oxazolidin-2-one with 1-substituted phenyl-2H-pyrazolin-3-one. Their structures were confirmed and characterized by 1H-NMR, 13C-NMR, elemental analysis, and mass spectroscopy. In addition, the crystal structure of the target compound 3-(2-((1-phenyl-2H-pyrazol-3-yloxy)methyl)phenyl) oxazolidin-2-one was determined by single crystal X-ray diffraction. The bioassay results of these compounds indicated that some of the oxazolidin-2-one derivatives containing N-substituted phenyl 2H-pyrazol ring exhibited potential in vivo fungicidal activities against M. grisea at the dosage of 1 g L-1.