1940-28-9

Basic information

• Product Name: Phenol, 4-broMo-3,5-dichloro-
• Synonyms: Phenol, 4-broMo-3,5-dichloro-
• CAS NO: 1940-28-9
• Molecular Formula: C₆H₃BrCl₂O
• Molecular Weight: 241.89742
• Mol File: 1940-28-9.mol
• Article Data: 6

Chemical Properties

• Melting Point: 121-123 °C
• Boiling Point: 304.4±37.0 °C(Predicted)
• Appearance: /
• Density: 1.890±0.06 g/cm3(Predicted)
• PKA: 7.49±0.23(Predicted)
• CAS DataBase Reference: Phenol, 4-broMo-3,5-dichloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-broMo-3,5-dichloro-(1940-28-9)
• EPA Substance Registry System: Phenol, 4-broMo-3,5-dichloro-(1940-28-9)

Safety Data

• Hazardous Substances Data: 1940-28-9(Hazardous Substances Data)

Usage

General Description

4-bromo-3,5-dichloro-phenol is a chemical compound with the molecular formula C6H3BrCl2O. It is a derivative of phenol, containing two chlorine atoms and one bromine atom attached to the benzene ring. Phenol, 4-bromo-3,5-dichloro- is commonly used as a building block in the synthesis of pharmaceuticals, dyes, and other organic compounds. It is also used as a disinfectant and antiseptic due to its antimicrobial properties. Additionally, 4-bromo-3,5-dichloro-phenol is used in the production of pesticides and as an intermediate in the manufacturing of other industrial chemicals. Due to its potential health and environmental effects, proper handling and disposal procedures are important when working with this compound.

Upstream product

• 591-35-5 3,5-dichlorophenol 
• 139-66-2 diphenyl sulfide 
• 19393-92-1 1-bromo-2,6-dichlorobenzene 
• 942069-45-6 2-(4-bromo-3,5-dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Downstream Products

• 145797-33-7 2,6-dichloro-4-[2-(2-naphthalenyloxy)ethoxy]-alpha-oxobenzeneacetic acid methyl ester 
• 1259428-75-5 4-bromo-3,5-dichlorophenyl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranoside 

Relevant articles and documents

Practical one-pot C-H activation/borylation/oxidation: Preparation of 3-bromo-5-methylphenol on a multigram scale

A practical one-pot C-H activation/borylation/oxidation sequence for the generation of 3,5-disubstituted phenols is presented. Specifically, 3-bromo-5-methylphenol is prepared from 3-bromotoluene, without isolation of intermediates, on a multigram scale, and in high yield. The process proceeds under mild conditions and can be completed within one day. Georg Thieme Verlag Stuttgart - New York.

Structure-Based Approach to Identify 5-[4-Hydroxyphenyl]pyrrole-2-carbonitrile Derivatives as Potent and Tissue Selective Androgen Receptor Modulators

In an effort to find new and safer treatments for osteoporosis and frailty, we describe a novel series of selective androgen receptor modulators (SARMs). Using a structure-based approach, we identified compound 7, a potent AR (ARE EC50 = 0.34 nM) and selective (N/C interaction EC50 = 1206 nM) modulator. In vivo data, an AR LBD X-ray structure of 7, and further insights from modeling studies of ligand receptor interactions are also presented.

C-H activation/borylation/oxidation: A one-pot unified route to meta-substituted phenols bearing ortho-/para-directing groups

An efficient one-pot C-H activation/borylation/oxidation protocol for the preparation of phenols is described. This method is particularly attractive for the generation of meta-substituted phenols bearing ortho-/para-directing groups, as such substrates are difficult to access by other phenol syntheses. Copyright