1940-28-9

Usage

Uses

Used in Pharmaceutical Industry:
Phenol, 4-bromo-3,5-dichlorois used as a building block in the synthesis of pharmaceuticals for its ability to contribute to the development of new drug molecules. Its unique structure allows it to be a key intermediate in the creation of various medicinal compounds.
Used in Dye Industry:
In the dye industry, Phenol, 4-bromo-3,5-dichlorois utilized as a precursor in the production of dyes. Its chemical properties make it suitable for the synthesis of a range of colorants used in different applications.
Used in Disinfection and Antiseptics:
Phenol, 4-bromo-3,5-dichlorois employed as a disinfectant and antiseptic due to its antimicrobial properties. It helps in controlling the growth of microorganisms, making it useful in healthcare and sanitation applications.
Used in Pesticide Production:
Phenol, 4-bromo-3,5-dichlorois also used in the production of pesticides, where its chemical structure aids in the development of effective agents for controlling pests in agriculture.
Used as an Industrial Chemical Intermediate:
Phenol, 4-bromo-3,5-dichloroserves as an intermediate in the manufacturing of other industrial chemicals, contributing to the synthesis of a variety of chemical products used across different sectors.

Upstream product

• 942069-45-6 2-(4-bromo-3,5-dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 591-35-5 3,5-dichlorophenol 
• 139-66-2 diphenyl sulfide 
• 19393-92-1 1-bromo-2,6-dichlorobenzene 

Downstream Products

• 145797-33-7 2,6-dichloro-4-[2-(2-naphthalenyloxy)ethoxy]-alpha-oxobenzeneacetic acid methyl ester 
• 1259428-75-5 4-bromo-3,5-dichlorophenyl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranoside 

Relevant academic research and scientific papers

Practical one-pot C-H activation/borylation/oxidation: Preparation of 3-bromo-5-methylphenol on a multigram scale

A practical one-pot C-H activation/borylation/oxidation sequence for the generation of 3,5-disubstituted phenols is presented. Specifically, 3-bromo-5-methylphenol is prepared from 3-bromotoluene, without isolation of intermediates, on a multigram scale, and in high yield. The process proceeds under mild conditions and can be completed within one day. Georg Thieme Verlag Stuttgart - New York.

COMPOUNDS AND METHODS OF PROMOTING MYELINATION

The present invention relates to a method of promoting myelination of central nervous system neurons in a subject suffering from a myelin-related disorder, the method comprising administering to the subject a therapeutically effective amount of a compound

Structure-Based Approach to Identify 5-[4-Hydroxyphenyl]pyrrole-2-carbonitrile Derivatives as Potent and Tissue Selective Androgen Receptor Modulators

In an effort to find new and safer treatments for osteoporosis and frailty, we describe a novel series of selective androgen receptor modulators (SARMs). Using a structure-based approach, we identified compound 7, a potent AR (ARE EC50 = 0.34 nM) and selective (N/C interaction EC50 = 1206 nM) modulator. In vivo data, an AR LBD X-ray structure of 7, and further insights from modeling studies of ligand receptor interactions are also presented.

Process for the synthesis of phenols from arenes

A process to synthesize substituted phenols such as those of the general formula RR′R″Ar(OH) wherein R, R′, and R″ are each independently hydrogen or any group which does not interfere in the process for synthesizing the substituted phenol including, but not limited to, halo, alkyl, alkoxy, carboxylic ester, amine, amide; and Ar is any variety of aryl or hetroaryl by means of oxidation of substituted arylboronic esters is described. In particular, a metal-catalyzed C—H activation/borylation reaction is described, which when followed by direct oxidation in a single or separate reaction vessel affords phenols without the need for any intermediate manipulations. More particularly, a process wherein Ir-catalyzed borylation of arenes using pinacolborane (HBPin) followed by oxidation of the intermediate arylboronic ester by OXONE is described.

C-H activation/borylation/oxidation: A one-pot unified route to meta-substituted phenols bearing ortho-/para-directing groups

An efficient one-pot C-H activation/borylation/oxidation protocol for the preparation of phenols is described. This method is particularly attractive for the generation of meta-substituted phenols bearing ortho-/para-directing groups, as such substrates are difficult to access by other phenol syntheses. Copyright

Novel halogenated phenol esters, antimicrobial compositions containing them and their use

Halogenated phenol esters of the formula STR1 wherein X represents chlorine or fluorine and R represents hydrogen, alkyl of 1 to 22 carbon atoms, alkenyl of 2 to 22 carbon atoms, benzyl which is unsubstituted or substituted by chlorine or bromine atoms, o