194032-35-4

Usage

Uses

Used in Pharmaceutical Industry:
TETRT-BUTYL3-METHYL-1,4-DIAZEPANE-1-CARBOXYLATE is used as an intermediate in the synthesis of pharmaceutical compounds for its unique structural features that can contribute to the development of new drugs with specific biological activities.
Used in Chemical Industry:
In the chemical industry, TETRT-BUTYL3-METHYL-1,4-DIAZEPANE-1-CARBOXYLATE serves as a reagent or building block in the organic synthesis of various chemical products, leveraging its diazepane ring and carboxylate ester group for creating complex molecular structures.

InChI:InChI=1/C11H22N2O2/c1-9-8-13(7-5-6-12-9)10(14)15-11(2,3)4/h9,12H,5-8H2,1-4H3

Upstream product

• 65974-17-6 2-Methyl-hexahydro-1H-1,4-diazepine 
• 1001401-67-7 tert-butyl 4-benzyl-3-methyl-1,4-diazepane-1-carboxylate 

Downstream Products

• 1001401-68-8 tert-butyl 3-methyl-4-(5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl)-1,4-diazepane-1-carboxylate 

Relevant academic research and scientific papers

SUBSTITUTED DIAZEPAN OREXIN RECEPTOR ANTAGONISTS

The present invention is directed to substituted diazepan compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.

ISOQUINOLINESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT

This invention relates to isoquinolinesulfonamide derivatives represented by the following formula (1): wherein A represents a linear or branched alkylene group, R1 represents a hydrogen atom, an hydroxyl, alkoxy or alkyl group or the like, R2 represents a hydrogen atom, an alkyl group or the like, R3 represents a hydrogen atom, an alkyl group or the like, and R4 and R5 may be the same or different and individually represent hydrogen atoms or lower alkyl groups; N-oxides and salts thereof; and solvates thereof. This invention is also concerned with pharmaceutical compositions, which contain the derivatives, N-oxides, salts, or solvates. These derivatives, N-oxides, salts, and solvates have viral proliferation inhibiting activities and are useful as AIDS therapeutics.

Isoquinoline derivatives and drugs

PCT No. PCT/JP97/00240 Sec. 371 Date Jul. 29, 1998 Sec. 102(e) Date Jul. 29, 1998 PCT Filed Jan. 31, 1997 PCT Pub. No. WO97/28130 PCT Pub. Date Aug. 7, 1997The invention relates to a compound of the following general formula [I] or a medicinally acceptable salt thereof, or a solvate thereof, wherein R1 represents alkyl, alkenyl, alkynyl, alkoxy, hydroxy, cyano, or halogen; R2 represents hydrogen, hydroxy, or halogen; R3 represents hydrogen, alkyl, or amidino; Ring A represents a 5 to 11-membered cyclic amino group which may be substituted, which cyclic amino group may be bridged between two carbon atoms in optional positions. The compound of this invention is useful for the prevention or treatment of cerebral tissue impairment due to the vasospasm following cerebral hemorrhage.