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N-[(8R)-1-azabicyclo[2.2.2]oct-8-yl]-2-oxo-9-thia-5-azabicyclo[4.3.0]nona-3,7,10-triene-3-carboxamide hydrochloride, commonly known as Cimaglermin, is a chemical compound that functions as a potent and selective agonist for the growth hormone secretagogue receptor. It is recognized for its ability to stimulate the release of growth hormone, which positions it as a promising therapeutic agent for various medical conditions.

194093-42-0

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194093-42-0 Usage

Uses

Used in Endocrinology:
Cimaglermin is utilized as a treatment for growth hormone deficiency, a condition characterized by insufficient levels of growth hormone in the body. Its agonistic action on the growth hormone secretagogue receptor helps to increase growth hormone levels, thereby addressing the deficiency.
Used in Treatment of Cachexia:
Cimaglermin is also applied in the management of cachexia, a severe wasting disorder often associated with chronic diseases such as cancer and AIDS. By enhancing growth hormone release, it can potentially improve muscle mass and overall body composition in cachectic patients.
Used in Cardiology:
In the field of cardiology, Cimaglermin has been investigated for its potential to improve cardiac function and promote repair of tissue damage subsequent to a heart attack. The growth hormone release induced by Cimaglermin may contribute to the enhancement of heart function and regeneration of damaged cardiac tissue.
Ongoing research continues to explore the applications of N-[(8R)-1-azabicyclo[2.2.2]oct-8-yl]-2-oxo-9-thia-5-azabicyclo[4.3.0]nona-3,7,10-triene-3-carboxamide hydrochloride in various medical fields, with a focus on its therapeutic potential in endocrinology and cardiology.

Check Digit Verification of cas no

The CAS Registry Mumber 194093-42-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,0,9 and 3 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 194093-42:
(8*1)+(7*9)+(6*4)+(5*0)+(4*9)+(3*3)+(2*4)+(1*2)=150
150 % 10 = 0
So 194093-42-0 is a valid CAS Registry Number.
InChI:InChI=1/C15H17N3O2S.ClH/c19-13-10(7-16-11-3-6-21-14(11)13)15(20)17-12-8-18-4-1-9(12)2-5-18;/h3,6-7,9,12H,1-2,4-5,8H2,(H,16,19)(H,17,20);1H/t12-;/m0./s1

194093-42-0 Well-known Company Product Price

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  • Sigma

  • (SML1038)  MKC-733  ≥98% (HPLC)

  • 194093-42-0

  • SML1038-5MG

  • 1,232.01CNY

  • Detail
  • Sigma

  • (SML1038)  MKC-733  ≥98% (HPLC)

  • 194093-42-0

  • SML1038-25MG

  • 4,966.65CNY

  • Detail

194093-42-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-7-oxo-4H-thieno[3,2-b]pyridine-6-carboxamide,hydrochloride

1.2 Other means of identification

Product number -
Other names (R)-N-(1-azabicyclo[2.2.2]oct-3-yl)-7-oxo-4,7-dihydrothieno-[3,2-b]pyridine-6-carboxamide hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:194093-42-0 SDS

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