194095-02-8Relevant academic research and scientific papers
Intense fluorescence of 1-aryl-2,3,4,5-tetraphenylphosphole oxides in the crystalline state
Fukazawa, Aiko,Ichihashi, Yasunori,Yamaguchi, Shigehiro
, p. 1537 - 1540 (2010)
A series of 2,3,4,5-tetraphenylphosphole oxides with various aryl groups on the phosphorus atoms were synthesized and their fluorescence properties in the crystalline state were investigated. Some of these compounds showed an intense fluorescence with the
Incorporation of phosphole moieties into the side chain of tyrosine and phenylalanine
Bisaro, Fabrice,Lefloch, Pascal
experimental part, p. 3081 - 3085 (2011/02/26)
A tyrosine derivative with a phosphole moiety covalently attached to the phenolic hydroxy group was successfully prepared through P-O bond-forming reaction, via a nucleophilic substitution reaction at the phosphorus, by slow addition of N-CBz-protected tyrosine methyl ester to a chlorophosphole adduct in the presence of triethylamine, albeit with a low yield. Furthermore, a phenylalanine derivative with a phosphole-containing side chain was conveniently synthesized by Stille cross-coupling reaction of a stannylphosphole reagent with N-Boc-protected 4-iodophenylalanine methyl ester, using Pd(dba)2 as catalyst, in the absence of any additional ligand. These molecules must be seen as valuable building blocks for the preparation of metalloproteins of interest for chemical, biological, and medical applications
