194150-84-0Relevant academic research and scientific papers
Aminoacrylates. II. An efficient synthesis of α-pyridones by heterocyclic annelation reactions of magnesium amides derived from sec- aminoacrylates with methyl propiolate
Koike, Takeshi,Takeuchi, Naoki,Tobinaga, Seisho
, p. 128 - 130 (1999)
The reactions of magnesium amides 4 derived from sec-aminoacrylates 3 and ethylmagnesium bromide with methyl propiolate (2) afforded α-pyridones. This provides an efficient heterocyclic annelation reaction.
Domino reaction of arylamine, methyl propiolate, aromatic aldehyde, and indole for facile synthesis of functionalized indol-3-yl acrylates
Zhang, Li-Li,Sun, Jing,Yan, Chao-Guo
, p. 6965 - 6967 (2013/01/15)
In the presence of FeCl3 as catalyst the one-pot domino reactions of arylamines, methyl propiolate, aromatic aldehydes, and indole in ethanol at room temperature proceeded smoothly to give methyl 2-(1H-indol-3-yl)arylmethyl-3-arylamino)acrylate
Synthesis of functionalized 2-aminohydropyridines and 2-pyridinones via domino reactions of arylamines, methyl propiolate, aromatic aldehydes, and substituted acetonitriles
Sun, Jing,Sun, Yan,Xia, Er-Yan,Yan, Chao-Guo
experimental part, p. 436 - 441 (2011/10/08)
An efficient and practical synthetic method for the functionalized 2-amino hydropyridines and 2-pyridinones was successfully developed via the domino reactions of arylamines, methyl propiolate, aromatic aldehydes and the substituted acetonitriles with tri
Aminoenylesters. I. A new synthesis of 1,2,3,4-tetrahydropyrimidines by heterocyclic annelation reactions of aminoenylesters with primary amines and acetaldehyde
Koike, Takeshi,Tanabe, Mituharu,Takeuchi, Naoki,Tobinaga, Seisho
, p. 1117 - 1119 (2007/10/03)
The reactions of aminoenylesters 3, which were prepared by the reactions of methyl propiolate (1) and primary amines 2, with primary amines 2 and acetaldehyde afforded 1,2,3,4-tetrahydropyrimidines 4. This provides a new heterocyclic annelation reaction.
