194159-18-7 Usage
Uses
Used in Antiviral Applications:
Ganciclovir Monoproprionate is used as an antiviral agent for the treatment of various viral infections. It exhibits anti-viral activity through experimental studies, making it a valuable addition to the arsenal of medications used to combat viral diseases.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Ganciclovir Monoproprionate is used as a prodrug to enhance the delivery and bioavailability of Ganciclovir. This allows for more effective treatment of viral infections and potentially reduces the side effects associated with the parent drug.
Used in Research and Development:
Ganciclovir Monoproprionate is also utilized in research and development for the study of viral mechanisms and the development of new antiviral drugs. Its unique properties make it an interesting compound for further investigation and potential application in the field of virology.
Check Digit Verification of cas no
The CAS Registry Mumber 194159-18-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,1,5 and 9 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 194159-18:
(8*1)+(7*9)+(6*4)+(5*1)+(4*5)+(3*9)+(2*1)+(1*8)=157
157 % 10 = 7
So 194159-18-7 is a valid CAS Registry Number.
194159-18-7Relevant academic research and scientific papers
NMR spectral data for ester prodrugs of ganciclovir
Gao, Hongwu,Mitra, Ashim K.
, p. 696 - 700 (2007/10/03)
A series of 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine mono- and diesters, 2a-i, 3a-d and 4a-d, were synthesized as potential prodrugs of ganciclovir and both 1H NMR and 13C NMR spectra were assigned to these esters based on spectral comparison with compounds of similar structure. Copyright
Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
-
, (2008/06/13)
Process and novel intermediates for preparing the mono-L-valine ester of 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol ganciclovir) and its pharmaceutically acceptable salts. The present process and monoester intermediates provide for mono-esterification by an L-valine derivative, resulting in a monocarboxylate-monovalinate which is then selectively hydrolyzed under basic or enzymatic conditions to give the monovaline ester of ganciclovir in high yield and purity. These products are of value as antiviral agents with improved absorption.
