194159-88-1Relevant academic research and scientific papers
Synthesis of fluorosugar analogues of 2,5,6-trichloro-1-(β-D- ribofuranosyl)benzimidazole as antivirals with potentially increased glycosidic bond stability
Gudmundsson, Kristjan S.,Freeman, George A.,Drach, John C.,Townsend, Leroy B.
, p. 2473 - 2478 (2000)
The metabolic instability in vivo of the glycosidic bond of 2,5,6- trichloro-1-(β-D-ribofuranosyl)benzimidazole (TCRB) prompted us to design and synthesize the hitherto unreported fluorinated benzimidazole nucleosides 2,5,6-trichloro-1-(2-deoxy-2-fluoro-β
Modified benzimidazole nucleosides as antiviral agents
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, (2008/06/13)
This invention pertains to nucleoside analogs which have antiviral activity and improved metabolic stability. More specifically, this invention pertains to modified sugar benzimidazole nucleosides, as exemplified by compounds such as benzimidazole nucleos
