194163-91-2 Usage
Description
N-BOC-TRANS-4-CYANO-L-PROLINE METHYL ESTER is a chemical compound derived from proline, an essential amino acid in proteins. It features a tert-butoxycarbonyl (BOC) protecting group, a nitrile functional group, and a methyl ester group attached to the carboxylic acid of proline. N-BOC-TRANS-4-CYANO-L-PROLINE METHYL ESTER plays a crucial role in organic synthesis and is a valuable building block in the production of pharmaceuticals and biologically active molecules.
Uses
Used in Pharmaceutical Industry:
N-BOC-TRANS-4-CYANO-L-PROLINE METHYL ESTER is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and functional groups enable the development of new drugs with improved therapeutic properties.
Used in Organic Synthesis:
In the field of organic synthesis, N-BOC-TRANS-4-CYANO-L-PROLINE METHYL ESTER serves as a versatile building block for the creation of complex organic molecules. Its presence of the BOC protecting group allows for selective reactions, while the nitrile and methyl ester groups provide additional sites for further functionalization.
Used in the Production of Biologically Active Molecules:
N-BOC-TRANS-4-CYANO-L-PROLINE METHYL ESTER is utilized in the synthesis of biologically active molecules, such as peptides, proteins, and other bioactive compounds. Its incorporation into these molecules can enhance their biological activity and potential applications in medicine and research.
Check Digit Verification of cas no
The CAS Registry Mumber 194163-91-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,1,6 and 3 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 194163-91:
(8*1)+(7*9)+(6*4)+(5*1)+(4*6)+(3*3)+(2*9)+(1*1)=152
152 % 10 = 2
So 194163-91-2 is a valid CAS Registry Number.
194163-91-2Relevant articles and documents
Efficient α-helix induction in a linear peptide chain by n-capping with a bridged-tricyclic diproline analogue
Hack, Verena,Reuter, Cédric,Opitz, Robert,Schmieder, Peter,Beyermann, Michael,Neud?rfl, J?rg-Martin,Kühne, Ronald,Schmalz, Hans-Günther
, p. 9539 - 9543 (2013)
Secondary structure induction: The synthetic tricyclic amino acid ProM-5, which is formally created by stereoselective introduction of a vinylidene bridge into a di-proline unit, acts as a powerful scaffold to nucleate α-helix formation in a linear peptide chain. This might be exploited in the development of new proteomimetics for the modulation of protein interactions. Copyright