19418-11-2

Basic information

• Product Name: 2-Thiophenecarboxylic acid, tetrahydro-
• Synonyms: 2-Thiophenecarboxylic acid, tetrahydro-;tetrahydrothiophene-2-carboxylic acid;Tetrahydro-2-thiophenecarboxylic acid;thiolane-2-carboxylic acid;(2R,5S)-5-(4-Amino-5-Fluoro-2-Oxo-2H-Pyrimidin-Yl)-(1,3)-Oxa - Thiolane-2-Carboxylic Acid,2S-Isopropyl-5R-Methyl-1R-Cyclo
• CAS NO: 19418-11-2
• Molecular Formula: C₅H₈O₂S
• Molecular Weight: 132.18
• Mol File: 19418-11-2.mol

Chemical Properties

• Melting Point: 53 °C
• Boiling Point: 291.4±33.0 °C(Predicted)
• Appearance: /
• Density: 1.315±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 3.60±0.20(Predicted)
• CAS DataBase Reference: 2-Thiophenecarboxylic acid, tetrahydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiophenecarboxylic acid, tetrahydro-(19418-11-2)
• EPA Substance Registry System: 2-Thiophenecarboxylic acid, tetrahydro-(19418-11-2)

Safety Data

• Hazardous Substances Data: 19418-11-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Thiophenecarboxylic acid, tetrahydrois used as an intermediate in the synthesis of various pharmaceuticals for its antimicrobial, antifungal, and antiviral properties. It contributes to the development of new drugs targeting a range of infections and diseases.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Thiophenecarboxylic acid, tetrahydrois used as a building block in the production of various agrochemicals, including neonicotinoid insecticides. Its incorporation enhances the effectiveness of these insecticides, providing a more sustainable approach to pest control.
Used in Organic Chemistry:
2-Thiophenecarboxylic acid, tetrahydrois utilized as a versatile building block in the synthesis of a wide range of organic compounds. Its unique structure and properties make it a valuable component in the development of new chemical entities with potential applications in various industries.

Upstream product

• 18342-42-2 tetrahydro-thiophene-2-carboxylic acid ethyl ester 
• 26551-57-5 ethyl [(3-chloropropyl)thio]acetate 
• 13679-75-9 1-thiophen-2-yl-propan-1-one 
• 88-15-3 2-Acetylthiophene 
• 112212-93-8 (3-Chloropropylthio)acetonitrile 
• 98486-29-4 5-chloro-2-mercapto-valeric acid methyl ester 
• 527-72-0 2-thiophenylcarboxylic acid 
• 112212-94-9 tetrahydrothiophene-2-carbonitrile 

Downstream Products

• 822-67-3 Cyclohex-2-enol 
• 112213-02-2 Tetrahydrothiophene-2-carboxanilide 
• 146036-18-2 5,10,15,20-tetrakisporphyrin 
• 63521-95-9 tetrahydrothiophene-2-carbonyl chloride 

Relevant articles and documents

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A photosynthetic bacterium, which can grow photosynthetically on benzoate, was isolated from sewage mud.Various kinds of aromatic compounds including heterocyclic aromatic compounds were photometabolized by the washed cells grown photosynthetically on benzoate with no lag period.Among these, thiophene-2-carboxylate was metabolized most rapidly to its (+)- tetrahydro derivative.The same strain could also grow on succinate under photosynthetic conditions.However, thiophene-2-carboxylate was only photometabolized after a long lag period by the washed cells grown photosynthetically on succinate, and the metabolite was not its (+)-tetrahydro derivative but (+)-3-hydroxytetrahydrothiophene-2-carboxylate.In the presence of chloramphenicol, an inhibitor of protein synthesis, the photometabolism of thiophene-2-carboxylate by the washed cells grown photosynthetically on benzoate was not affected at all, but the photometabolism of the same substrate by the washed cells grown photosynthetically on succinate was completely inhibited.These results indicate that a reduction system of broad substrate specificity for aromatic rings is already present in the benzoate-grown cells but absent in the succinate-grown cells.It seems that such a reduction system for aromatic rings is induced by an aromatic substrate.