194225-52-0

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrafluoro-2-[1-(4-nitrophenyl)ethyl]-, (S)-
• CAS NO: 194225-52-0
• Molecular Formula: C16H8F4N2O4
• Molecular Weight: 368.244
• Mol File: 194225-52-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrafluoro-2-[1-(4-nitrophenyl)ethyl]-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrafluoro-2-[1-(4-nitrophenyl)ethyl]-, (S)-(194225-52-0)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrafluoro-2-[1-(4-nitrophenyl)ethyl]-, (S)-(194225-52-0)

Safety Data

• Hazardous Substances Data: 194225-52-0(Hazardous Substances Data)

Upstream product

• 652-12-0 4,5,6,7-tetrafluoroisobenzofuran-1,3-dione 
• 4187-53-5 (S)-1-(p-nitrophenyl)ethylamine 

Downstream Products

• 194225-54-2 (S)-2-[1-(4-aminophenyl)ethyl]-4,5,6,7-tetrafluoro-1H-isoindole-1,3-dione 

Relevant articles and documents

Novel biological response modifiers: Phthalimides with tumor necrosis factor-α production-regulating activity

Novel N-substituted phthalimides (2-substituted 1H-isoindole-1,3- diones) were prepared, and their effects on tumor necrosis factor-α (TNF- α) production by human leukemia cell line HL-60 stimulated with 12-O- tetradecanoylphorbol 13-acetate (TPA) or okadaic acid (OA) were examined. A structure-activity relationship study of the N-phenylphthalimides and N- benzylphthalimides revealed that their enhancing effect on TPA-induced TNF- α production by HL-60 cells and their inhibiting effect on OA-induced TNF- α production by HL-60 cells are only partially correlated.