194286-86-7Relevant academic research and scientific papers
Heteroaryl analogues of AMPA. Synthesis and quantitative structure- activity relationships
Bang-Andersen, Benny,Lenz, Sibylle M.,Skj?rb?k, Niels,S?by, Karina K.,Hansen, Hans O.,Ebert, Bjarke,B?ges?, Klaus P.,Krogsgaard-Larsen, Povl
, p. 2831 - 2842 (2007/10/03)
A number of 3-isoxazolol bioisosteres, 7a-i, of (S)-glutamic acid (Glu), in which the methyl group of (RS)-2-amino-3-(3-hydroxy-5-methylisoxazol-4- yl)propionic acid (AMPA, 1) was replaced by different 5-membered heterocyclic rings, were synthesized. Comp
