194294-76-3

Upstream product

• 194294-67-2 (3S,5R)-3-Hydroxy-1-((S)-4-isopropyl-2-thioxo-thiazolidin-3-yl)-5-(4-methoxy-benzyloxy)-6-(2-trimethylsilanyl-ethoxymethoxy)-hexan-1-one 
• 76513-69-4 (2-trimethylethylsilylethoxy)methyl chloride 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 194294-64-9 (R)-4-Hydroxy-N-methoxy-3-(4-methoxy-benzyloxy)-N-methyl-butyramide 
• 194294-66-1 (R)-3-(4-Methoxy-benzyloxy)-4-(2-trimethylsilanyl-ethoxymethoxy)-butyraldehyde 
• 194294-75-2 (R)-N-Methoxy-3-(4-methoxy-benzyloxy)-N-methyl-4-(2-trimethylsilanyl-ethoxymethoxy)-butyramide 

Downstream Products

• 194294-71-8 (2R,4S,8S,10R)-4-(tert-Butyl-diphenyl-silanyloxy)-8-hydroxy-2,10-bis-(4-methoxy-benzyloxy)-1-(2-trimethylsilanyl-ethoxymethoxy)-tridec-12-en-6-one 
• 194294-80-9 (2R,4S,8S,10R)-4-(tert-Butyl-diphenyl-silanyloxy)-2,10-bis-(4-methoxy-benzyloxy)-8-triethylsilanyloxy-1-(2-trimethylsilanyl-ethoxymethoxy)-tridec-12-en-6-one 
• 194294-68-3 (4S,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-(4-methoxy-benzyloxy)-7-(2-trimethylsilanyl-ethoxymethoxy)-heptan-2-one 
• 194294-81-0 (2R,4S,6R,8R,10S)-2-Allyl-10-(tert-butyl-diphenyl-silanyloxy)-8-(2-trimethylsilanyl-ethoxymethoxymethyl)-1,7-dioxa-spiro[5.5]undecan-4-ol 
• 194294-77-4 (3S,5R)-3-(tert-Butyl-diphenyl-silanyloxy)-5-(4-methoxy-benzyloxy)-6-(2-trimethylsilanyl-ethoxymethoxy)-hexanoic acid methoxy-methyl-amide 

Relevant academic research and scientific papers

A modular approach to marine macrolide construction. 2. Concise stereocontrolled synthesis of the C17-C28 (CD) spiroacetal component

The CD spiroacetal ring system of altohyrtin A, which houses one-fifth of the stereogenic centers resident in the macrolide, has been synthesized through a combination of aldol condensations having different stereocontrol elements.