194302-48-2

Upstream product

• 36982-84-0 2,4,6-Triisopropylbenzenesulfonyl azide 
• 194302-64-2 (1R,2S)-1,2-bis[2-oxo-2-((4S)-benzyl-2-oxo-3-oxazolidinyl)ethyl]cyclopropane 
• 2345-68-8 ((1R,2S)-2-Hydroxymethyl-cyclopropyl)-methanol 
• 702-28-3 1,2-cyclopropane dicarboxylic acid diester 
• 194302-62-0 ((1S,2R)-2-Chlorocarbonylmethyl-cyclopropyl)-acetyl chloride 
• 158771-89-2 cis-1,2-di(bromomethyl)cyclopropane 
• 54010-19-4 trans-Cyclopropyl-diessigsaeure-(1,2) 
• 89693-69-6 cis-1,2-Cyclopropan-diacetonitril 
• 59014-42-5 (cis-cyclopropane-1,2-diyl)-di-acetic acid 
• 89693-69-6 ((1S,2S)-2-Cyanomethyl-cyclopropyl)-acetonitrile 
• 82442-59-9 ((1S*,2S*)-cyclopropane-1,2-diyl)dimethanol 

Downstream Products

• 194302-52-8 ((S)-2-((S)-4-Benzyl-2-oxo-oxazolidin-3-yl)-1-{(1S,2S)-2-[(S)-2-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-1-tert-butoxycarbonylamino-2-oxo-ethyl]-cyclopropyl}-2-oxo-ethyl)-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Stereoselective synthesis of cyclopropane-1,2-bis(glycine) derivatives

Conformationally constrained bis(glycines) as trans derivatives of cyclopropane have been prepared in stereoselective syntheses. (S)-4-Benzyl-2-oxazolidinone was used as a chiral auxiliary, trisyl azide was the electrophilic source of amine nitrogen. Four stereogenic centers were created. A related cis-cyclopropane derivative suffered ring closure with formation of a bicyclo[3.1.0]hex-3-one derivative. X-ray data for the latter and for (1S,2S)-1,2-bis{(1S)-azido-2-oxo-2[(4S)-benzyl-2-oxo-3-oxazolidinyl] -ethyl}cyclopropane are presented.