19433-93-3Relevant articles and documents
A 3 - (N, N - disubstituted) amino acetophenone compound of clean production method
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Paragraph 0042-0045, (2017/08/31)
The invention relates to a clean production method of 3-(N,N-di-substituted)aminoacetanilide compounds (III). The method comprises the following steps: (1) adding water to a compound of Formula (I), stirring uniformly, adding alkali to regulate the pH value to 6-7 when the substituent group R1 is hydrogen or not regulating the pH value when the substituent group R1 is methoxy group, adding a compound of Formula (II) and an acid-binding agent, and reacting to the end point while controlling the pH value at 4-9 and the temperature at 60-130 DEG C; (2) separating out a compound (III) to obtain a chloride salt-containing mother solution; (3) decolorizing the chloride salt-containing mother solution by using activated carbon or by adsorbing organic matters with a resin, thereby obtaining a colorless chloride salt mother solution; and (4) recovering the chloride salt from the colorless chloride salt mother solution by MVR (mechanical vapor recompression) high-efficiency concentration cooling crystallization or multiple-effect evaporation system concentration crystallization, wherein the concentration condensation water and crystallization mother solution are respectively recycled. The method lowers the production cost, and implements resource recovery and reduction on wastewater.
