194353-51-0Relevant articles and documents
New neplanocin analogues. VIII. Synthesis and biological activity of 6'- C-ethyl, -ethenyl, and -ethynyl derivatives of neplanocin A
Shuto, Satoshi,Obara, Takumi,Saito, Yasuyoshi,Yamashita, Kanako,Tanaka, Motohiro,Sasaki, Takuma,Andrei, Graciela,Snoeck, Robert,Neyts, Johan,Padalko, Elisabeth,Balzarini, Jan,De Clercq, Erik,Matsuda, Akira
, p. 1163 - 1168 (2007/10/03)
This report describes the synthesis and antiviral effects of (6'R)-6'- C-ethynyl, -ethenyl, and -ethyl derivatives of neplanocin A (7a, 8a, and 9a, respectively) and the corresponding 6'S-diastereomers (7b, 8b, and 9b, respectively), as examples of 6'-C-s