194367-33-4

Upstream product

• 194367-31-2 Acetic acid (R)-1-{(2S,3S)-1-benzyl-2-[(S)-1-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-oxo-azetidin-3-yl}-ethyl ester 
• 194367-41-4 (E)-4-(tert-Butyl-diphenyl-silanyloxy)-pent-2-enoic acid tert-butyl ester 
• 161554-86-5 (2S,3S,4S)-2-((R)-1-Acetoxy-ethyl)-3-benzylamino-4-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid tert-butyl ester 
• 194367-32-3 Acetic acid (R)-1-[(2S,3S)-1-benzyl-2-((S)-1-hydroxy-ethyl)-4-oxo-azetidin-3-yl]-ethyl ester 

Relevant academic research and scientific papers

Highly Diastereoselective Conjugate Addition of Lithium Dialkylamides to α,β-Unsaturated Esters Having a Chiral Center at the γ-Position

The conjugate addition of lithium amides 2 to tert-butyl 4-(OR)-substituted-2-pentenoates 1 produced a mixture of the syn- and anrt-amino esters (3 and 4) in high yields. Sterically bulky OR groups, such as trityloxy and tert-butyldiphenylsilyloxy, gave t