194412-38-9

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 194412-34-5 methyl 3-azido-3,5-dideoxy-5-C-diethoxyphosphinyl-β-D-xylofuranoside 
• 194412-32-3 methyl 5-deoxy-5-C-diethoxyphosphinyl-β-D-ribofuranoside 
• 194412-33-4 methyl 5-deoxy-5-C-diethoxyphosphinyl-2,3-O-sulfinyl-β-D-ribofuranoside 
• 194412-37-8 methyl 5-deoxy-5-C-diethoxyphosphinyl-β-D-ribofuranoside-2,3-sulfate 

Relevant academic research and scientific papers

Synthesis of 2,3-aziridino-2,3-dideoxy-D-lyxono-γ-lactone 5-phosphonate from D-ribose, a new member of the 2,3-aziridino-γ-lactone family of synthons

A formal synthesis of the novel (1S,4S,5R)-N-(benzyloxycarbonyl(-4-diethoxyphosphinyl)methyl-3-oxa-6 -azabicyclo[3.1.0]hexan-2-one 4 from D-ribose is presented. A key step involves the use of the 2,3-sulfate 12 for introduction of the C-3 azide functionality prior to aziridine ring formation.