19442-79-6

Upstream product

• 4720-83-6 6-oxabicyclo<3.2.1>-oct-3-en-7-one 
• 54911-89-6 cis-methyl 5-hydroxycyclohex-3-enecarboxylate 
• 87830-10-2 trans-5-(methoxycarbonyl)-2-cyclohexenyl chloride 
• 19914-92-2 (+/-)-4-iodo-6-oxabicyclo[3.2.1]octan-7-one 
• 4771-80-6 1,2,5,6-tetrahydrobenzoic acid 

Relevant academic research and scientific papers

Asymmetric palladium-catalyzed allylic alkylation using dialkylzinc reagents: A remarkable ligand effect

A serendipitously discovered palladium-catalyzed asymmetric allylic alkylation reaction with diorganozinc reagents, which displays broad functional group compatibility, is reported. This novel transformation hinges on a remarkable ligand effect which overrides the standard "umpolung" reactivity of allyl-palladium intermediates in the presence of dialkylzincs. Owing to its mild conditions, enantioselective allylic alkylations of racemic allylic electrophiles are possible in the presence of sensitive functional groups. Umpole-me-not: A serendipitously discovered palladium-catalyzed asymmetric allylic alkylation reaction with diorganozinc reagents displays broad functional group compatibility. This novel transformation hinges on a remarkable ligand effect which overrides the standard "umpolung" reactivity of allyl-palladium intermediates in the presence of dialkylzinc compounds.