194423-20-6

Upstream product

• 194423-19-3 (E)-(R)-8-Benzyloxy-1-chloro-5-hydroxy-oct-1-en-3-one 
• 54125-02-9 danishefsky's diene 
• 5470-84-8 4-benzyloxybutanal 

Downstream Products

• 194423-21-7 (2R,4S)-2-(3-Benzyloxy-propyl)-3,4-dihydro-2H-pyran-4-ol 
• 1026393-78-1 (2R,6R)-2-(3-Benzyloxy-propyl)-6-(3,3-dibromo-allyl)-3,6-dihydro-2H-pyran 
• 194423-22-8 Acetic acid (2R,4S)-2-(3-benzyloxy-propyl)-3,4-dihydro-2H-pyran-4-yl ester 
• 194423-26-2 (2R,6R)-2-(3-Benzyloxy-propyl)-6-but-2-ynyl-3,6-dihydro-2H-pyran 
• 194423-23-9 [(2R,6R)-6-(3-Benzyloxy-propyl)-5,6-dihydro-2H-pyran-2-yl]-acetaldehyde 
• 194423-25-1 (2R,6R)-2-(3-Benzyloxy-propyl)-6-prop-2-ynyl-3,6-dihydro-2H-pyran 

Relevant academic research and scientific papers

Synthesis of trans-syn-trans fused bis-pyrans via endo-selective cyclizations of cyclic sulfates

Acid-catalyzed cyclization of hydroxy-cyclic sulfates occurs with endo- regioselectivity affording bispyran products from substrates in which the nucleophilic hydroxyl and electrophilic cyclic sulfate groups are 1,2-trans- substituted on a cyclic pyran template. This methodology is demonstrated in an enantioselective synthesis of the trans-syn-trans fused AB cyclic ether rings of the brevetoxin natural products.