194468-47-8Relevant academic research and scientific papers
Generation and trapping of cyclopropyldiazonium and diazocyclopropane in the nitrosation of cyclopropylamine with alkyl nitrites
Tomilov,Okonnishnikova,Shulishov,Nefedov
, p. 671 - 675 (2007/10/03)
Diazocyclopropane and an cyclopropyldiazonium ion, which are highly reactive intermediates, can be generated and trapped by appropriate substrates immediately in the direct nitrosation of cyclopropylamine with alkyl nitrites. Diazocyclopropane is trapped
Addition of diazocyclopropane generated in situ to acrylic acid derivatives and transformations of resulting functionally substituted spiro(pyrazolinecyclopropanes)
Tomilov,Kostyuchenko,Shulishov,Nefedov
, p. 511 - 518 (2007/10/03)
The reaction of diazocyclopropane generated in situ with acrylonitrile or methyl acrylate to give 1 : 1, 1 : 2, and 2 : 1 cycloadducts was carried out. The products resulting from 1.3-dipolar cycloaddition and subsequent isomerization, viz., 3-cyano- and 3-methoxycarbonylspiro(2-pyrazoline-5,1 ′-cyclopropanes), isolated in the first step in -70% yield, react in an alkaline solution with the above acrylates or diazocyclopropane as C(3)-nucleophiles to give the corresponding 3-(2′-cyanoethyl)-, 3-(2′-methoxycarbonylethyl)-, or 3-(cyclopropylazo)-1-pyrazolines. The thermal deazotization of these pyrazolines to spiropentane derivatives was investigated.
