194474-79-8Relevant articles and documents
Tricyclic heteroaromatic systems. 3-Substituted 1,2,3,5,6,7-hexahydro- 2,5,6-trioxopyrazino[1,2,3-de]-quinoxalines as novel antagonists at the glycine-NMDA site
Varano,Catarzi,Colotta,Cecchi,Filacchioni,Galli,Costagli
, p. 179 - 182 (2007/10/03)
Two novel antagonists of the glycine-NMDA receptor have been synthesized and tested for their ability to displace [3H]glycine from its specific binding site in rat brain cortical membranes. The 3-substituted pyrazino[1,2,3-de]quinoxalin-2,5,6-t