194547-17-6

Basic information

• Product Name: 7-{4-nitrophenyl}-3,4-diphenyl-6-(1-pyrrolidinyl)pyrimido[4',5':4,5]thieno[2,3-c]pyridazin-8(7H)-one
• Synonyms: 7-{4-nitrophenyl}-3,4-diphenyl-6-(1-pyrrolidinyl)pyrimido[4',5':4,5]thieno[2,3-c]pyridazin-8(7H)-one
• CAS NO: 194547-17-6
• Molecular Formula: C30H22N6O3S
• Molecular Weight: 546.59908
• Mol File: 194547-17-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-{4-nitrophenyl}-3,4-diphenyl-6-(1-pyrrolidinyl)pyrimido[4',5':4,5]thieno[2,3-c]pyridazin-8(7H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-{4-nitrophenyl}-3,4-diphenyl-6-(1-pyrrolidinyl)pyrimido[4',5':4,5]thieno[2,3-c]pyridazin-8(7H)-one(194547-17-6)
• EPA Substance Registry System: 7-{4-nitrophenyl}-3,4-diphenyl-6-(1-pyrrolidinyl)pyrimido[4',5':4,5]thieno[2,3-c]pyridazin-8(7H)-one(194547-17-6)

Safety Data

• Hazardous Substances Data: 194547-17-6(Hazardous Substances Data)

Upstream product

• 100-28-7 4-Nitrophenyl isocyanate 
• 128462-42-0 ethyl 5-amino-3,4-diphenylthieno[2,3-c]pyridazine-6-carbohydrazide 
• 94011-79-7 3-chloro-5,6-diphenylpyridazine-4-carbonitrile 
• 194546-83-3 5-{[N-(4-Nitro-phenyl)-pyrrolidine-1-carboximidoyl]-amino}-3,4-diphenyl-thieno[2,3-c]pyridazine-6-carboxylic acid ethyl ester 
• 194546-63-9 ethyl 3,4-diphenyl-5-(triphenylphosphoranilydeneamino)thieno[2,3-c]pyridazine-6-carboxylate 

Relevant articles and documents

An efficient synthesis for pyrimido[4′,5′:4,5]-thieno[2,3-c]pyridazine derivatives via intramolecular AZA-wittig reaction-heterocyclization strategy

A ready one-pot preparation for substituted pyrimidothienopyridazines is reported. Aza-Wittig reaction of iminophosphorane (3), derived from ethyl 5-amino-3,4-diphenylthieno[2,3-c]pyridazine-6-carboxylate (2), with isocyanates, followed by heterocyclization on addition of amines provided a novel synthetic route to the functionalized pyrimido[4′,5′:4,5]thieno[2,3-c]pyridazines (6). The guanidine-type intermediate compounds (5) derived from addition of amines to the carbodiimides (4) could be isolated and characterized, thus confirming the suggest reaction pathway.