194551-76-3Relevant articles and documents
A stereocontrolled, convergent synthesis of hydroxyethylene dipeptide isosteres
Tao, Junhua,Hoffman, Robert V.
, p. 6240 - 6244 (1997)
A simple, convergent, and stereoselective synthesis of hydroxyethylene dipeptide isosteres 1 and 2 from scalemic α-hydroxy esters has been developed. The method is short (six steps), efficient (?15-25% overall), and highly diastereoselective (86-94% de) and enantioselective (>95% ee).