19458-46-9

Basic information

• Product Name: 20,26-dihydroxyecdysone
• Synonyms: 20,26-dihydroxyecdysone;(22R)-2β,3β,14,20,22,25,26-Heptahydroxy-5β-cholest-7-en-6-one;Podecdysone C
• CAS NO: 19458-46-9
• Molecular Formula: C₂₇H₄₄O₈
• Molecular Weight: 496.63
• Mol File: 19458-46-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 750.4°Cat760mmHg
• Flash Point: 421.5°C
• Appearance: /
• Density: 1.33g/cm³
• Vapor Pressure: 5.47E-26mmHg at 25°C
• Refractive Index: 1.611
• PKA: 14.13±0.70(Predicted)
• CAS DataBase Reference: 20,26-dihydroxyecdysone(CAS DataBase Reference)
• NIST Chemistry Reference: 20,26-dihydroxyecdysone(19458-46-9)
• EPA Substance Registry System: 20,26-dihydroxyecdysone(19458-46-9)

Safety Data

• Hazardous Substances Data: 19458-46-9(Hazardous Substances Data)

Usage

Chemical classification

20,26-dihydroxyecdysone is an ecdysteroid, a type of steroid hormone found in insects and various plants.

Sources

The compound has been identified in several plant species, including some traditional Chinese medicinal herbs.

Pharmacological activities

20,26-dihydroxyecdysone has shown potential anti-inflammatory, anti-tumor, and anti-diabetic properties.

Effects on muscle growth

The compound has demonstrated positive effects on muscle growth and metabolism.

Relevance to sports nutrition

Due to its effects on muscle growth and metabolism, 20,26-dihydroxyecdysone is of interest for research in sports nutrition and performance enhancement.

Therapeutic potential

The unique biological activities and potential therapeutic applications of 20,26-dihydroxyecdysone make it a promising candidate for further scientific investigation and development of new pharmaceutical agents.

InChI:InChI=1/C27H44O8/c1-23(33,14-28)8-7-22(32)26(4,34)21-6-10-27(35)16-11-18(29)17-12-19(30)20(31)13-24(17,2)15(16)5-9-25(21,27)3/h11,15,17,19-22,28,30-35H,5-10,12-14H2,1-4H3/t15-,17-,19+,20-,21-,22+,23?,24+,25+,26+,27?/m0/s1

Upstream product

• 3604-87-3 ecdysone 
• 13408-48-5 ponasterone A 
• 52717-49-4 26-hydroxyecdysone 
• 84507-66-4 20-hydroxyecdysone 2,3:20,22-diacetonide 

Related news

Naturally occurring 20,26-dihydroxyecdysone (cas 19458-46-9) exists as two C-25 epimers which exhibit different degrees of moulting hormone activity08/17/2019

20,26-Dihydroxyecdysone (20,26-ECD) isolated from Vitex canescens, V. glabrata and V. pinnata has been shown to exist as two C-25 epimers. Synthesis and separation of the two epimers were accomplished and they exhibited different degree of moulting hormone activity in the Musca assay.detailed

Relevant articles and documents

Naturally occurring 20, 26-dihydroxyecdysone exists as two C-25 epimers which exhibit different degrees of moulting hormone activity

20,26-Dihydroxyecdysone (20,26-ECD) isolated from Vitex canescens, V. glabrata and V. pinnata has been shown to exist as two C-25 epimers. Synthesis and separation of the two epimers were accomplished and they exhibited different degree of moulting hormone activity in the Musca assay.

High-performance liquid chromatography of ecdysone metabolites applied to the cabbage butterfly, Pieris brassicae L.

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