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(S)-3-Benzyl-8-oxa-2-aza-spiro[4.5]decan-1-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

194598-53-3

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194598-53-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 194598-53-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,5,9 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 194598-53:
(8*1)+(7*9)+(6*4)+(5*5)+(4*9)+(3*8)+(2*5)+(1*3)=193
193 % 10 = 3
So 194598-53-3 is a valid CAS Registry Number.

194598-53-3Downstream Products

194598-53-3Relevant academic research and scientific papers

Novel spirocyclic pyrrolidones as P2/P1 mimetics in potent inhibitors of HIV-1 protease.

Kazmierski, Wieslaw M,Furfine, Eric,Spaltenstein, Andrew,Wright, Lois L

, p. 3431 - 3433 (2007/10/03)

We have developed concise and efficient syntheses of novel spirocyclic pyrrolidones 1-3, which involve the alkylation of pyrrolidone precursor 13 with 1,5-dibromopentane, 16 and 15, followed by an in situ lactamization. Conjugates of 1 and 2 with P1'/P2' hydroxy-indanolamine moiety resulted in novel and potent inhibitors of HIV-1 protease 25 and 26, suggesting that 1 and 2 are novel P2/P1 HIV-PI mimetics.

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