194658-52-1 Usage
Uses
Used in Cosmetic and Personal Care Industry:
Sulfamic acid, 4-(4-oxohexadecyl)phenyl ester is used as an intermediate for the production of various cosmetic and personal care products, contributing to their formulation and enhancing their performance.
Used in Industrial and Household Cleaning Products:
In the cleaning industry, Sulfamic acid, 4-(4-oxohexadecyl)phenyl ester is used as a corrosion inhibitor, helping to prevent damage to metal surfaces during the cleaning process.
Used in Descaling Agents and Metal Cleaning Solutions:
Sulfamic acid, 4-(4-oxohexadecyl)phenyl ester is used as an active ingredient in descaling agents and metal cleaning solutions, where it effectively removes scale and rust from metal surfaces.
Used in Specialty Cleaners and Detergents:
In the formulation of specialty cleaners and detergents, Sulfamic acid, 4-(4-oxohexadecyl)phenyl ester acts as a surfactant, aiding in the breakdown and removal of tough stains and soils, thus improving the cleaning efficacy of these products.
Check Digit Verification of cas no
The CAS Registry Mumber 194658-52-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,6,5 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 194658-52:
(8*1)+(7*9)+(6*4)+(5*6)+(4*5)+(3*8)+(2*5)+(1*2)=181
181 % 10 = 1
So 194658-52-1 is a valid CAS Registry Number.
194658-52-1Relevant academic research and scientific papers
Structure-activity relationship studies of the amide functionality in (p-O-sulfamoyl)-N-alkanoyl tyramines as estrone sulfatase inhibitors
Chu, Guo-Hua,Milano, Shawn,Kluth, Lisa,Rhodes, Michael,Boni, Riccardo,Johnson, David A.,Li, Pui-Kai
, p. 530 - 535 (2007/10/03)
Recently, we reported the synthesis and biochemical studies of a series of (p-O-sulfamoyl)-N-alkanoyl tyramines as nonsteroidal estrone sulfatase inhibitors. One of the most potent inhibitors in this series is (p-O- sulfamoyl)-N-tridecanoyl tyramine 1 with an IC50 value of 61.3 nM. In this study, we synthesized four analogs of 1 (compounds 2-5) to investigate the structure-activity relationships of the amide functionality in (p-O- sulfamoyl)-N-tridecanoyl tyramine. Replacement of the amide functionality in 1 with an ethylene moiety to form the alkyl analog 5 resulted in complete loss of sulfatase inhibitory activity (IC50 of 61.3 nM vs. >20 μM). The keto, hydroxy, and ester analogs (inhibitors 2-4) are 8-15 times less in affinity to the sulfatase than inhibitor 1. However, their inhibitory activities are significantly higher than the alkyl analog 5. The results suggest that the amide functionality is favorable for sulfatase inhibitory activity and that there may be a hydrogen bonding component to the enzyme interaction in this region.
