194720-31-5

Basic information

• Product Name: C₇₀H₉₄N₂O₁₄Si₂
• Synonyms: C₇₀H₉₄N₂O₁₄Si₂
• CAS NO: 194720-31-5
• Molecular Weight: 1243.69
• Mol File: 194720-31-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₇₀H₉₄N₂O₁₄Si₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₇₀H₉₄N₂O₁₄Si₂(194720-31-5)
• EPA Substance Registry System: C₇₀H₉₄N₂O₁₄Si₂(194720-31-5)

Safety Data

• Hazardous Substances Data: 194720-31-5(Hazardous Substances Data)

Upstream product

• 194720-29-1 C₄₈H₆₉NO₉Si₂ 
• 194720-28-0 C₄₂H₆₃NO₉Si₂ 
• 194720-25-7 C₄₀H₆₀BrNO₈Si₂ 
• 194720-27-9 C₄₀H₆₁NO₈Si₂ 
• 194720-24-6 C₃₃H₅₃BrO₉Si₂ 
• 194720-22-4 C₃₃H₅₇BrO₉Si₂ 
• 100-46-9 benzylamine 
• 591-51-5 phenyllithium 
• 155396-69-3 (2R,4S,5R)-(2R,4S,5R)-3-tert-butoxycarbonyl-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-5-carboxylic acid 
• 194720-30-4 C₄₈H₇₁NO₉Si₂ 

Downstream Products

• 194720-17-7 C₅₀H₆₀N₂O₁₃ 

Relevant articles and documents

Synthesis and Biological Evaluation of D-Ring-Modified Taxanes:1 5(20)-Azadocetaxel Analogs

Two 5(20)-aza analogs of docetaxel, N-20-benzyl-5(20)-azadocetaxel (5) and 5(20)-azadocetaxel (6), have been synthesized from 10-deacetylbaccatin III. The key steps of this synthesis involved the direct introduction of a C-5 leaving group while ring opening and the intramolecular nucleophilic attack of the C-20 amino group at C-5. Both compounds were inactive on the in vitro cytotoxic assay, and only the azadocetaxel 6 retains an antitubulin activity, but 16 times less than docetaxel.