194736-62-4Relevant academic research and scientific papers
Broomeanamides: Cyclic Octapeptides from an Isolate of the Fungicolous Ascomycete Sphaerostilbella broomeanafrom India
Bills, Gerald F.,Ekanayake, Dulamini I.,Gloer, James B.,Perlatti, Bruno,Swenson, Dale C.,P?ldmaa, Kadri
, p. 2028 - 2034 (2021)
The genusSphaerostilbellacomprises fungi that colonize basidiomata of wood-inhabiting fungi, including important forest pathogens. Studies of fermentation cultures of an isolate (TFC201724) collected on the foothills of Himalayas, and closely related toS.
Anti-Cryptococcus Phenalenones and Cyclic Tetrapeptides from Auxarthron pseudauxarthron
Li, Yan,Yue, Qun,Jayanetti, Dinith R.,Swenson, Dale C.,Bartholomeusz, Geoffrey A.,An, Zhiqiang,Gloer, James B.,Bills, Gerald F.
supporting information, p. 2101 - 2109 (2017/08/04)
Auxarthrones A-E (1-5), five new phenalenones, and two new naturally occurring cyclic tetrapeptides, auxarthrides A (7) and B (8), were obtained from three different solvent extracts of cultures of the coprophilous fungus Auxarthron pseudauxarthron. Auxarthrones C (3) and E (5) possess an unusual 7a,8-dihydrocyclopenta[a]phenalene-7,9-dione ring system that has not been previously observed in natural products. Formation of 1-5 was found to be dependent on the solvent used for culture extraction. The structures of these new compounds were elucidated primarily by analysis of NMR and MS data. Auxarthrone A (1) was obtained as a mixture of chromatographically inseparable racemic diastereomers (1a and 1b) that cocrystallized, enabling confirmation of their structures by X-ray crystallography. The absolute configurations of 7 and 8 were assigned by analysis of their acid hydrolysates using Marfey's method. Compound 1 displayed moderate antifungal activity against Cryptococcus neoformans and Candida albicans, but did not affect human cancer cell lines.
Novel bioactive peptides, PF1171F and PF1171G, from unidentified ascomycete OK-128
Kuo, Yi-Hsuan,Kai, Kenji,Akiyama, Kohki,Hayashi, Hideo
experimental part, p. 429 - 431 (2012/02/03)
Two cyclic peptides, PF1171F (1) and PF1171G (2), were isolated from okara fermented with the unidentified ascomycete OK-128, and their structures were determined by NMR, MS, and Marfey amino acid analysis. Both peptides showed paralytic activity against
Determination of absolute structures of cyclic peptides, PF1171A and PF1171C, from unidentified ascomycete OK-128
Kai, Kenji,Yoshikawa, Hanae,Kuo, Yi-Hsuan,Akiyama, Kohki,Hayashi, Hideo
experimental part, p. 1309 - 1311 (2011/09/19)
Two cyclic peptides, PF1171A (1) and PF1171C (2), were isolated from okara that had been fermented with unidentified ascomycete OK-128. Their absolute configurations were determined by Marfey's method. These peptides showed paralytic activity against silkworms.
