194794-77-9

Upstream product

• 186395-69-7 (1R,4S,4aR,7R,7aS)-1-((S)-3-Isopropyl-cyclopent-1-enyl)-4,7-dimethyl-hexahydro-cyclopenta[c]pyran-3-one 
• 186395-86-8 (1R,3aS,4S,5R,6aR,7S,9aS,10aS)-7-Isopropyl-5-methoxymethoxy-1,4,9a-trimethyl-dodecahydro-dicyclopenta[a,d]cycloocten-10-one 
• 186395-71-1 (1R,3aS,4S,5R,6aR,7S,9aS,10aS)-7-Isopropyl-5-methoxymethoxy-1,4-dimethyl-dodecahydro-dicyclopenta[a,d]cycloocten-10-one 
• 186422-89-9 (S)-2-((1R,2S,3R)-2-Formyl-3-methyl-cyclopentyl)-propionic acid methyl ester 
• 120264-20-2 (R)-(+)-1-bromo-3-(1-methylethyl)cyclopentene 
• 194794-76-8 (1R,3aS,4S,5R,6aR,7S,9aS,10R,10aS)-7-Isopropyl-5-methoxymethoxy-1,4-dimethyl-tetradecahydro-dicyclopenta[a,d]cycloocten-10-ol 

Downstream Products

• 89002-20-0 Epoxydictymene 

Relevant academic research and scientific papers

Highly enantioselective total synthesis of natural epoxydictymene. An alkoxy-directed cyclization route to highly strained trans-oxabicyclo[3.3.0]octanes

An enantioselective synthesis of (+)-epoxydictymene, which involves efficient construction of the strained oxabicyclo[3.3.0]octane subunit by irradiation with iodosobenzene diacetate and iodine in cyclohexane solution, is reported.

Total synthesis of (+)-epoxydictymene. Application of alkoxy-directed cyclization to diterpenoid construction

An enantioselective synthesis of (+)-epoxydictymene (1) is reported. Condensation of the enantiopure aldehydo ester 5 with (S)-3-isopropylcyclopentenyllithium proceeds selectively to afford 13. Once this lactone was methylenated with the Tebbe reagent, th