194808-29-2Relevant academic research and scientific papers
A Selective Synthesis of 2-Arylamino-4H-1,3,4-thiadiazino[5,6-b]-quinoxalines and Mesoionic Triazolo[4,3-a]quinoxaline
Kim, Ho Sik,Kim, Tong Eun,Kwag, Sam Tag,Park, Yong Tae,Hong, Young Seuk,Okamoto, Yoshihisa,Kurasawa, Yoshihisa
, p. 1539 - 1542 (2007/10/03)
The reaction of the 6-chloro-2-(1-methyl-2-thiocarbamoylhydrazino)quinoxaline 4-oxides 3a-d with trifluoroacetic anhydride gave the 2-(N-aryl)trifluoroacetamido-8-chloro-4-methyl-4H-1,3,4-thiadiazino-[5,6-b] quinoxalines 7a-d, respectively, while the reflux of compounds 3a-c in N,N-dimethylformamide afforded the mesoionic triazolo[4,3-a]quinoxaline 4. Hydrolysis of compounds 7a-d with triethylamine/water provided the 2-arylamino-8-chloro-4-methyl-4H-1,3,4-thiadiazino[5,6-b]quinoxalines 8a-d, respectively.
