19484-26-5

Basic information

• Product Name: tridecane-1-thiol
• Synonyms: tridecane-1-thiol;Tridecan-1-thiol;Tridecyl thioalcohol;1-Mercaptotridecane;NSC 851
• CAS NO: 19484-26-5
• Molecular Formula: C₁₃H₂₈S
• Molecular Weight: 216.42642
• EINECS: 243-104-3
• Mol File: 19484-26-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 8.89°C
• Boiling Point: 291℃
• Flash Point: 112℃
• Appearance: /
• Density: 0.841
• Vapor Pressure: 0.00337mmHg at 25°C
• Refractive Index: 1.4586
• CAS DataBase Reference: tridecane-1-thiol(CAS DataBase Reference)
• NIST Chemistry Reference: tridecane-1-thiol(19484-26-5)
• EPA Substance Registry System: tridecane-1-thiol(19484-26-5)

Safety Data

• Hazardous Substances Data: 19484-26-5(Hazardous Substances Data)

Usage

General Description

Tridecane-1-thiol, also known as tridecanethiol, is a chemical compound with the formula C13H28S. It is a type of thiol compound, which is characterized by the presence of a sulfur atom bonded to a carbon atom. Tridecane-1-thiol is a colorless liquid with a strong, unpleasant odor, and it is insoluble in water but soluble in organic solvents. It is commonly used in the production of flavors and fragrances, as well as in chemical synthesis and as a reagent in various laboratory reactions. Additionally, tridecane-1-thiol has been found to have antimicrobial properties, making it useful in the development of antimicrobial agents and products.

InChI:InChI=1/C13H28S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14/h14H,2-13H2,1H3

Upstream product

• 765-09-3 1-bromotridecane 
• 17356-08-0 thiourea 

Downstream Products

• 2307-24-6 n-Tridecylthiomyristat 
• 2307-31-5 n-Tridecylthiopalmitat 

Relevant articles and documents

Odd-even effects in charge transport across n-alkanethiolate-based SAMs

This paper compares rates of charge transport across self-assembled monolayers (SAMs) of n-alkanethiolates having odd and even numbers of carbon atoms (nodd and neven) using junctions with the structure MTS/SAM//Ga2O3/EGaIn (M = Au or Ag). Measurements of current density, J(V), across SAMs of n-alkanethiolates on AuTS and AgTS demonstrated a statistically significant odd-even effect on AuTS, but not on AgTS, that could be detected using this technique. Statistical analysis showed the values of tunneling current density across SAMs of n-alkanethiolates on AuTS with nodd and neven belonging to two separate sets, and while there is a significant difference between the values of injection current density, J0, for these two series (log|J0Au,even| = 4.0 ± 0.3 and log|J0Au,odd| = 4.5 ± 0.3), the values of tunneling decay constant, β, for nodd and neven alkyl chains are indistinguishable (βAu,even = 0.73 ± 0.02 ?-1, and βAu,odd= 0.74 ± 0.02 ?-1). A comparison of electrical characteristics across junctions of n-alkanethiolate SAMs on gold and silver electrodes yields indistinguishable values of β and J0 and indicates that a change that substantially alters the tilt angle of the alkyl chain (and, therefore, the thickness of the SAM) has no influence on the injection current density across SAMs of n-alkanethiolates.

Intrinsic and Extrinsic Control of the p Ka of Thiol Guests inside Yoctoliter Containers

Despite decades of research, there are still many open questions surrounding the mechanisms by which enzymes catalyze reactions. Understanding all the noncovalent forces involved has the potential to allow de novo catalysis design, and as a step toward this, understanding how to control the charge state of ionizable groups represents a powerful yet straightforward approach to probing complex systems. Here we utilize supramolecular capsules assembled via the hydrophobic effect to encapsulate guests and control their acidity. We find that the greatest influence on the acidity of bound guests is the location of the acidic group within the yoctoliter space. However, the nature of the electrostatic field generated by the (remote) charged solubilizing groups also plays a significant role in acidity, as does counterion complexation to the outer surfaces of the capsules. Taken together, these results suggest new ways by which to affect reactions in confined spaces.

Identification of structural features of 2-alkylidene-1,3-dicarbonyl derivatives that induce inhibition and/or activation of histone acetyltransferases KAT3B/p300 and KAT2B/PCAF

Dysregulation of the activity of lysine acetyltransferases (KATs) is related to a variety of diseases and/or pathological cellular states; however, their role remains unclear. Therefore, the development of selective modulators of these enzymes is of paramount importance, because these molecules could be invaluable tools for assessing the importance of KATs in several pathologies. We recently found that diethyl pentadecylidenemalonate (SPV106) possesses a previously unobserved inhibitor/activator activity profile against protein acetyltransferases. Herein, we report that manipulation of the carbonyl functions of a series of analogues of SPV106 yielded different activity profiles against KAT2B and KAT3B (pure KAT2B activator, pan-inhibitor, or mixed KAT2B activator/KAT3B inhibitor). Among the novel compounds, a few derivatives may be useful chemical tools for studying the mechanism of lysine acetylation and its implications in physiological and/or pathological processes.