194856-17-2

Upstream product

• 2002-03-1 2-amino-5-phenyl-1,3,4-thiadiazole 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 856353-55-4 4-nitro-N-(5-phenyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide 

Relevant academic research and scientific papers

MODULATORS OF IMMUNOINHIBITORY RECEPTOR PD-1, AND METHODS OF USE THEREOF

Disclosed are an assay to identify modulators of the PD-1 :PD-L pathway and PD-1 :PD-L pathway modulators, e.g., compounds and pharmaceutical compositions thereof. Methods for treating diseases influenced by modulation of the PD-1 :PD-L pathway such as, for example, autoimmune diseases, inflammatory disorders, allergies, transplant rejection, cancer, immune deficiency, and other immune system-related disorders, are also disclosed.