194861-77-3

Basic information

• Product Name: 3-Oxazolidinecarboxylic acid, 4-[(1S,2R)-2-hydroxy-1-(phenylmethoxy)-3-hexadecynyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4S)-
• CAS NO: 194861-77-3
• Molecular Formula: C33H53NO5
• Molecular Weight: 543.788
• Mol File: 194861-77-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Oxazolidinecarboxylic acid, 4-[(1S,2R)-2-hydroxy-1-(phenylmethoxy)-3-hexadecynyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxazolidinecarboxylic acid, 4-[(1S,2R)-2-hydroxy-1-(phenylmethoxy)-3-hexadecynyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4S)-(194861-77-3)
• EPA Substance Registry System: 3-Oxazolidinecarboxylic acid, 4-[(1S,2R)-2-hydroxy-1-(phenylmethoxy)-3-hexadecynyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4S)-(194861-77-3)

Safety Data

• Hazardous Substances Data: 194861-77-3(Hazardous Substances Data)

Upstream product

• 194861-76-2 (S)-4-((S)-[1,3]Dithian-2-yl-hydroxy-methyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 102308-32-7 (4S)-4-formyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 765-10-6 1-tetradecyne 
• 115822-55-4 (4S,1'S)-4-(1'-benzyloxy-2'-oxoethyl)-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 

Relevant articles and documents

Stereocontrol in the addition of nucleophiles to an optically active aldehyde derived from L-serine, leading to a short-step synthesis of (2S,3S,4R)-phytosphingosine

The diastereoselective addition of dithianide to a chiral aldehyde derived from L-serine followed by hydrolysis of the dithiane moiety and the addition of dodecylacetylide gave diastereomerically pure aminotriol derivative which, upon hydrogenation and deprotection, afforded (2S,3S,4R)-phytosphingosine in good overall yield in enantiomerically pure form.