194876-61-4Relevant academic research and scientific papers
Aza-[3,3]-Claisen enolate rearrangement in vinylaziridines: Stereoselective synthesis of mono-, di-, and trisubstituted seven-membered lactams
Lindstroem, Ulf M.,Somfai, Peter
, p. 94 - 98 (2007/10/03)
Several 2,3-disubstituted vinylaziridines have been N-acylated and subjected to LiHMDS in THF at -78°C. Upon warming to room temperature, the resulting amide enolates underwent a highly stereoselective [3,3]-sigmatropic rearrangement to give mono-, di-, a
