194935-44-9Relevant academic research and scientific papers
Synthesis of Heterocyclic Analogues of Tamoxifen as Potential Antiestrogens
Srikanth, Natarajan,Tan, Choon-Hong,Ng, Siu-Choon,Loh, Teck-Peng,Koh, Lip-Lin,Sim, Keng-Yeow
, p. 1828 - 1849 (2007/10/03)
The synthesis of (E/Z)-1-aryl-2-phenyl-1-(2-thienyl/selenophen-2-yl)but-1-enes, derived from 2-phenyl-1-(2-thienyl-selenophen-2-yl)butan-1-ones is described.The key steps on the synthesis involve the reaction of the butan-1-ones with 4-(2-moprholinoethoxy)phenyl bromide, followed by dehydration of the resulting carbinols to give the target compounds which were separated by fractional recrystallization.
