194996-03-7

Basic information

• Product Name: Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-[2-[[(4-methoxyphenyl)methyl]amino] -2-oxoethyl]-
• CAS NO: 194996-03-7
• Molecular Formula: C17H24N2O6
• Molecular Weight: 352.387
• Mol File: 194996-03-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-[2-[[(4-methoxyphenyl)methyl]amino] -2-oxoethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-[2-[[(4-methoxyphenyl)methyl]amino] -2-oxoethyl]-(194996-03-7)
• EPA Substance Registry System: Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-[2-[[(4-methoxyphenyl)methyl]amino] -2-oxoethyl]-(194996-03-7)

Safety Data

• Hazardous Substances Data: 194996-03-7(Hazardous Substances Data)

Upstream product

• 56074-20-5 N-((tert-butyloxy)carbonyl)iminodiacetic acid 
• 2393-23-9 4-methoxy-benzylamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 56074-21-6 N-((tert-butyloxy)carbonyl)iminodiacetic acid anhydride 

Downstream Products

• 194996-27-5 [(4-Methoxy-benzylcarbamoyl)-methyl]-[(3,4,5-trimethoxy-benzylcarbamoyl)-methyl]-carbamic acid tert-butyl ester 
• 194996-10-6 {[2-(2,5-Dimethoxy-phenyl)-ethylcarbamoyl]-methyl}-[(4-methoxy-benzylcarbamoyl)-methyl]-carbamic acid tert-butyl ester 
• 194996-40-2 {[Bis-(2-methoxy-ethyl)-carbamoyl]-methyl}-[(4-methoxy-benzylcarbamoyl)-methyl]-carbamic acid tert-butyl ester 
• 194996-21-9 {[2-(3,4-Dimethoxy-phenyl)-ethylcarbamoyl]-methyl}-[(4-methoxy-benzylcarbamoyl)-methyl]-carbamic acid tert-butyl ester 
• 194996-51-5 {[3-(2,6-Dimethoxy-benzoylamino)-propylcarbamoyl]-methyl}-[(4-methoxy-benzylcarbamoyl)-methyl]-carbamic acid tert-butyl ester 
• 737828-54-5 N-((t-butyloxy)carbonyl)-N'-(4-methoxybenzyl)-N-1-(4-chlorobenzhydryl)piperazine iminodiacetic acid diamide 
• 305324-41-8 2-{[(tert-butoxy)carbonyl][2-(4-methylphenyl)-2-oxoethyl]amino}-N-(4-methoxybenzyl)acetamide 
• 211745-58-3 C₆₃H₈₃N₉O₁₈ 

Relevant articles and documents

Synthesis and evaluation of (4-chlorobenzhydryl) piperazine amides as sodium channel Nav1.7 inhibitors

Blockage of voltage-gated sodium channels is used to treat neuropathic pain which is chronic and can become debilitating. Sodium channels Nav1.7-1.9 are especially attractive targets for drug discovery because of the broad therapeutic potential of their m

Solution-phase combinatorial synthesis of nonpeptide bradykinin antagonists

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Higher order iminodiacetic acid libraries for probing protein-protein interactions

Full details of the preparation of iminodiacetic acid diamide dimer (2040 compounds), trimer (560 compounds), and tetramer (1596 compounds) libraries by multistep convergent solution-phase synthesis for studying protein-protein interactions are provided. The libraries were assembled in a format providing small 8-10 compound mixtures and the deconvolution of many of the small mixtures to identify screening leads by resynthesis of the individual components have been conducted for 320 of the individual compounds to date. A representative example of the subsequent exploration of the structure-activity relationships for an identified receptor binding antagonist (200 additional individual compounds) and steps taken for potential elaboration to a receptor dimerization agonist are defined with preparation of representative linked dimers (70 compounds). Copyright (C) 1998 Elsevier Science Ltd.