1951467-29-0 Usage
Description
[2-methyl-5-(β-D-glucopyranosyl)phenyl][5-(4-fluorophenyl)-2-thienyl]methanol, also known as (2S,3R,4R,5S,6R)-2-(3-((5-(4-Fluorophenyl)thiophen-2-yl)(hydroxy)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, is a complex organic compound characterized by its unique molecular structure. It is an impurity found in Canagliflozin, a medication used for treating type 2 diabetes.
Uses
Used in Pharmaceutical Industry:
[2-methyl-5-(β-D-glucopyranosyl)phenyl][5-(4-fluorophenyl)-2-thienyl]methanol is used as an impurity in the production of Canagliflozin (C175190), a sodium/glucose cotransporter 2 (SGLT2) inhibitor, for the treatment of type 2 diabetes. The presence of this compound in Canagliflozin is significant as it may affect the drug's efficacy, safety, and overall quality.
As an impurity in the pharmaceutical industry, [2-methyl-5-(β-D-glucopyranosyl)phenyl][5-(4-fluorophenyl)-2-thienyl]methanol is important for quality control and regulatory compliance. Ensuring that the levels of this impurity are within acceptable limits is crucial for maintaining the safety and effectiveness of Canagliflozin as a diabetes treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 1951467-29-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,9,5,1,4,6 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1951467-29:
(9*1)+(8*9)+(7*5)+(6*1)+(5*4)+(4*6)+(3*7)+(2*2)+(1*9)=200
200 % 10 = 0
So 1951467-29-0 is a valid CAS Registry Number.
1951467-29-0Relevant articles and documents
Canagliflozin impurity compound and preparation method thereof
-
Paragraph 0034; 0035, (2018/10/11)
The invention relates to a novel type 2 diabetes resistant drug canagliflozin impurity compound [2-methyl-5-(beta-D-glucopyranose)phenyl][5-(4-fluorophenyl)-2-thienyl]methyl hydroperoxide (a compoundof a formula IV) and a preparation method thereof, and application of the impurity compound serving as a canagliflozin quality control reference standard substance.
