195157-34-7

Basic information

• Product Name: (3R)-4-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3-(hydroxymethyl)butyl L-valinate
• Synonyms: (3R)-4-(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-(hydroxymethyl)butyl L-Valinate; L-Valine 4-Ester with 9-[(R)-4-Hydroxy-2-(hydroxymethyl)butyl]guanine; valomaciclovir
• CAS NO: 195157-34-7
• Molecular Formula: C₁₅H₂₄N₆O₄
• Molecular Weight: 352.3889
• Mol File: 195157-34-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 641.6°C at 760 mmHg
• Flash Point: 341.8°C
• Density: 1.51g/cm³
• Vapor Pressure: 2.45E-17mmHg at 25°C
• Refractive Index: 1.673
• CAS DataBase Reference: (3R)-4-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3-(hydroxymethyl)butyl L-valinate(CAS DataBase Reference)
• NIST Chemistry Reference: (3R)-4-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3-(hydroxymethyl)butyl L-valinate(195157-34-7)
• EPA Substance Registry System: (3R)-4-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3-(hydroxymethyl)butyl L-valinate(195157-34-7)

Safety Data

• Hazardous Substances Data: 195157-34-7(Hazardous Substances Data)

Usage

General Description

The chemical (3R)-4-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3-(hydroxymethyl)butyl L-valinate, also known as Valganciclovir, is an antiviral medication used to treat cytomegalovirus (CMV) infection. Valganciclovir is an oral prodrug of ganciclovir, which inhibits the replication of CMV by interfering with the viral DNA polymerase. Once ingested, Valganciclovir is converted to ganciclovir, which then acts to prevent the spread of the virus by inhibiting its ability to replicate. It is often used in patients with weakened immune systems, such as those with HIV/AIDS, organ transplant recipients, or individuals undergoing chemotherapy. Additionally, Valganciclovir may also be used for the treatment of CMV retinitis, a serious eye infection that can occur in individuals with HIV/AIDS.