195197-67-2

Upstream product

• 10316-53-7 4-phenyl-2,4,6-triazatricyclo[5.2.2.0^2,6]undec-8-ene-3,5-dione 
• 4233-33-4 4-Phenyl-1,2,4-triazolidine-3,5-dione 

Downstream Products

• 195197-73-0 N-((1S,2R,3S,4R)-2,3-Dihydroxy-4-phenylacetylamino-cyclohexyl)-2-phenyl-acetamide 

Relevant academic research and scientific papers

Biocatalysis in the chiral recognition of meso-diamides - An efficient route from cyclic olefinic hydrocarbons to optically pure diamino-polyols

meso-Diamino-di(tri,tetr)ols 1-8 were synthesized starting from cheap carbocyclic olefins and cis-diepoxy derivatives. Enantioselective hydrolysis of the corresponding bis(phenylacet)amides with penicillin amidase from E. coli (EC 3.5.1.11) was effected in good yields (73-90%) and with high optical purities (ee 91 - >97).