195197-98-9Relevant academic research and scientific papers
Novel synthesis and anti-inflammatory activities of 2,5-disubstituted- dioxacycloalkanes
Bi, Lanrong,Zhang, Yue,Zhao, Ming,Wang, Chao,Chan, Priscilla,Tok, Jeffrey B.-H.,Peng, Shiqi
, p. 5640 - 5646 (2007/10/03)
A novel stereospecific synthetic route to obtain a series of 2,5-disubstituted-dioxacycloalkanes is reported. Using an in vivo inhibition assay by monitoring xylene-induced ear edema in mice, the structure-activity relationship of the dioxacycloalkane com
Biocatalysis in the chiral recognition of meso-diamides - An efficient route from cyclic olefinic hydrocarbons to optically pure diamino-polyols
Grabowski, Stefan,Armbruster, Joachim,Prinzbach, Horst
, p. 5485 - 5488 (2007/10/03)
meso-Diamino-di(tri,tetr)ols 1-8 were synthesized starting from cheap carbocyclic olefins and cis-diepoxy derivatives. Enantioselective hydrolysis of the corresponding bis(phenylacet)amides with penicillin amidase from E. coli (EC 3.5.1.11) was effected in good yields (73-90%) and with high optical purities (ee 91 - >97).
