195244-97-4

Basic information

• Product Name: Cyclohexanepropanoic acid, a-[(9-phenyl-9H-fluoren-9-yl)amino]-, (S)-
• CAS NO: 195244-97-4
• Molecular Formula: C28H29NO2
• Molecular Weight: 411.544
• Mol File: 195244-97-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Cyclohexanepropanoic acid, a-[(9-phenyl-9H-fluoren-9-yl)amino]-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanepropanoic acid, a-[(9-phenyl-9H-fluoren-9-yl)amino]-, (S)-(195244-97-4)
• EPA Substance Registry System: Cyclohexanepropanoic acid, a-[(9-phenyl-9H-fluoren-9-yl)amino]-, (S)-(195244-97-4)

Safety Data

• Hazardous Substances Data: 195244-97-4(Hazardous Substances Data)

Upstream product

• 27527-05-5 L-cyclohexylalanine 
• 55135-66-5 9-bromo-9-phenyl-9H-fluorene 
• 17193-39-4 methyl 3-cyclohexyl-L-alaninate hydrochloride 

Relevant articles and documents

Enantiospecific Synthesis of N-9-Phenylfluoren-9-yl-α-amino Ketones

Enantiomerically pure N-(9-phenylfluoren-9-yl)-α-amino ketones were prepared in excellent yields by acylation of organolithium reagents with N-(9-phenylfluoren-9-yl)-α-amino acid-derived oxazolidinones. The method is not applicable for the acylation of Grignard reagents as they attack the methylenic carbon of the oxazolidinone to give the corresponding N-alkylated amino acids 13 in excellent yields. The resulting N-(9-phenylfluoren-9-yl)-α-amino ketones 8 could be stereoselectively reduced to the corresponding syn- or anti-β-amino alcohols depending upon the nature of the reducing agent.